Pharmacological targeting of netrin-1 inhibits EMT in cancer

Justine Lengrand (1, 2, 3) , Ievgenia Pastushenko (1) , Sebastiaan Vanuytven (4) , Yura Song (1) , David Venet (1, 5) , Rahul Sarate (1) , Melanie Bellina (2, 3) , Virginie Moers (1) , Alice Boinet (1) , Alejandro Sifrim (4) , Nicolas Rama (3) , Benjamin Ducarouge (2) , Jens van Herck (4) , Christine Dubois (1) , Samuel Scozzaro (1) , Sophie Lemaire (1) , Sarah Gieskes (1) , Sophie Bonni (1) , Amandine Collin (1) , Nicolas Braissand (2, 3) , Justine Allard (1) , Egor Zindy (1) , Christine Decaestecker (1) , Christos Sotiriou (1, 5) , Isabelle Salmon (1) , Patrick Mehlen (2, 3) , Thierry Voet (4) , Agnès Bernet (2, 3) , Cédric Blanpain (1)

1 ULB - Université libre de Bruxelles
2 Netris Pharma
3 UNICANCER/CRCL - Centre de Recherche en Cancérologie de Lyon
4 KU Leuven - Catholic University of Leuven = Katholieke Universiteit Leuven
5 Institut Jules Bordet [Bruxelles]

Domains: Cancer

Justine Lengrand, Ievgenia Pastushenko, Sebastiaan Vanuytven, Yura Song, David Venet, et al.. Pharmacological targeting of netrin-1 inhibits EMT in cancer. Nature, 2023, 620 (7973), pp.402-408. ⟨10.1038/s41586-023-06372-2⟩. ⟨hal-04238408⟩